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Peer Review PendingIn the early 21st century, endocrinologist Daniel Drucker asked for a hormone that mimicked the appetite-inhibiting and blood sugar-controlling action of human glucagon-like peptide-1 (GLP-1) yet would not be quickly broken down in the body

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Given the absence of mitochondria in mature RBCs to fuel beta-oxidation, the conjugation of free FAs and carnitine generates the acyl-carnitine pools that RBCs use to replace damaged membrane lipid acyl chains

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The SURMOUNT-2 trial enrolled participants with obesity and type 2 diabetes

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