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Both phase 2 trials involving PT-141 dosed at 1.75 mg have concluded that it is safe and well-tolerated

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After reconstitution with bacteriostatic water, refrigerate at 1-6 C and protect from light

Eating when physically hungry (not out of habit) becomes the new baseline, often reducing daily intake to 1,200-1,600 calories without willpower or restriction

127 Thus, the Duchenne muscular dystrophy is a primary genetic astrocytopathy that impairs synaptic transmission, causes excitotoxicity and secondary neurodegeneration