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Similar lean-mass proportion is not the same as builds muscle or preserves all muscle automatically. Across obesity treatment generally, lean body mass loss still occurs with weight reduction, including with GLP-1based therapies, and newer expert commentary continues to emphasize muscle preservation as a major clinical priority

Research indicates lean body mass can account for 15 to 40 percent of total weight lost on GLP-1 therapy

Its manufacturer, Janssen Pharmaceuticals, a subsidiary of Johnson & Johnson, has not issued any Elmiron recalls or pulled the drug from the market