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Cotadutide, a glucagon-like protein-1 receptor (GLP-1R) and glucagon receptor (GCGR) agonist, was shown to reduce blood glycaemia, body weight and hepatic steatosis in people with type 2 diabetes mellitus

However, analysis of semen samples from men with T1D showed that compared with non-diabetic fertile men, the semen mRNA profile of these patients showed altered expression of 21 genes, many involved in stress response, DNA metabolism, and replication/repair (Mallidis et al

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Anna Lembke, a Stanford University addiction medicine specialist