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Instead of using standard water, the formulators chose to lead the composition with 22.7% Centella Asiatica extract

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Interactions with Benzodiazepines and Other CNS Depressants Inform patients and caregivers that potentially fatal additive effects may occur if Oxycodone and Acetaminophen Tablets are used with benzodiazepines and other CNS depressants including alcohol (e.g., non-benzodiazepine-, sedative/hypnotics, anxiolytics, tranquilizers, muscle relaxants, general anesthetics, antipsychotics, gabapentinoids [gabapentin or pregabalin], and other opioids), and not to use these concomitantly unless supervised by a health care provider [see WARNINGS,PRECAUTIONS;Drug Interactions]

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