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The evidence base remains limited, and dietary modifications should focus on established patterns recommended by NICE and Diabetes UK, with allulose as an optional sugar substitute rather than a treatment

Therefore, the combined metabolic and functional disruptions in DAAs and reactive astrocytes exacerbate neuronal dysfunction, cellular pathophysiology, and cell death, contributing to progression in CNS pathology

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TABLE 2 The antiepileptic properties of plant extract and purified phytochemicals through the modulation of the glutamatergic pathway (especially NMDARs and AMPARs)