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This difference in efficiency is in line with the improved cellular uptake of phenformin over metformin and the much lower typical therapeutic dosage of phenformin compared to metformin in humans 68

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Brain Fog and Cognitive Dysfunction: The Omega-3 fatty acids (EPA and DHA) provide the building blocks for anti-inflammatory resolvins, which help downregulate microglial activation and neuroinflammation, potentially improving focus, memory retrieval, and mental clarity

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