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In pancreatic cancer, Gln confers resistance to tumor necrosis factor-associated apoptosis-inducing ligand (TRAIL) in pancreatic ductal adenocarcinoma (PDAC) cells through KDM4C-mediated epigenetic regulation of cFLIP

The isothiocyanates produced from the breakdown of glucosinolates by the action of the enzyme myrosinase [95] are highly electrophilic, a property of a compound that makes it readily available for the nucleophilic GSH when in the presence of GST [96]

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