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In this review, we discuss how these two G-protein coupled receptor (GPCR) ligands may improve L-DOPA-based treatment with minimized side effects or provide alternative nondopaminergic options for patients who would benefit from early treatment

The article says tesofensine blocks the reuptake of norepinephrine, dopamine, and serotonin in the brain, while tirzepatide activates GLP-1 and GIP receptors in the gut and brain

The study found that people using these drugs had fewer psychiatric hospital visits and took less time off work due to mental health issues

A Denver Doctors Guide to Food Cravings Food cravings are an intense desire for a specific food, characterized by a strong urge to consume it