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10.1371/journal.pone.0123454 89 SucicM.LueticK.JandricI.DrmicD.SeverA

The Bigger Picture The arrival of GLP-1 drugs represents a philosophical shift in how veterinarians approach obesity

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These tradeoffs are not merely theoretical: in the pilot phase of the PRECIDENTD pragmatic trial, participants assigned to dual therapy had substantially lower medication fill rates and higher discontinuation than those on monotherapy, driven largely by side effects, cost, and access [36]