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& Lazdunski, M

doi:10.1146/annurev.med.60.041807.123308 [16] Varga EA, Sturm AC, Misita CP, Moll S

Our findings of increased serum palmitoyl-L-carnitine with aging are consistent with observations in heart failure and coronary artery disease [56], where elevated levels likely result from disrupted mitochondrial fatty acid oxidation and impaired -oxidation, leading to acylcarnitine accumulation [57]