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As expected, NTg female mice fed any of the three diets performed well at the NOR test with a positive DI and no difference between groups (Fig

But theres a critical result the headlines largely skipped: The apitegromab group was not measurably stronger

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Case 2: A Bardet-Biedl syndrome patient with lifelong hyperphagia underwent combination therapy with 3mg setmelanotide and 5mg tirzepatide, leading to a severe food aversion, even to protein shakes, limiting their intake to fewer than 800 Calories daily