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Both medications work by stimulating GLP-1 receptors in the brain, slowing digestion and increasing fullness, which naturally lowers calorie intake and supports consistent, gradual fat loss over time
Schizophr Bull 47(5):13201330 Rentschler KM et al (2024) Reducing brain kynurenic acid synthesis precludes kynurenine-induced sleep disturbances
GLP-1 also signals appetite centers in the brain, indicating a sense of fullness during and between meals by slowing gastric emptying
Fluvoxamine but not citalopram increases serum melatonin in healthy subjects-an indication that cytochrome P450 CYP1A2 is involved in melatonin metabolism in man
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