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Additional class-related concerns include: Gallbladder disease , including cholelithiasis (gallstones) and cholecystitis, as observed with GLP-1 receptor agonist medicines [27] Dehydration and acute kidney injury (AKI) risk secondary to significant gastrointestinal fluid losses Increased heart rate , a recognised class effect of GLP-1 receptor agonists Pancreatitis a potential risk that warrants prompt medical assessment if severe abdominal pain develops Thyroid C-cell tumours observed in rodent studies with GLP-1 receptor agonists

3.4 Depression and anxiety Depression and anxiety are found in over 50% of patients with L-C19, especially due to hospitalization or cognitive disorders (60)

Brigelius-Floh R, Floh L

The injections may cause severe allergic reactions in the patient