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Resmetirom (Rezdiffra TM ), a liver-directed thyroid hormone receptor- (THR-) agonist, received accelerated FDA approval in March 2024 as the first agent specifically indicated for non-cirrhotic MASH with moderate-to-advanced fibrosis (F2-F3), based on the MAESTRO-NASH trial demonstrating MASH resolution and fibrosis improvement

The interesting question is what each company is actually doing : whether theyre making the drug, selling it, both, or simply renting out their distribution to someone who has already done the harder work

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4c), showing in an animal model that AG-120 disrupts redox balance in tumor cells