Scientifically, menopause triggers a sharp drop in estrogen, leading to vulvovaginal atrophy (thinning and drying of tissues), while chronic stress activates the hypothalamic-pituitary-adrenal axis, inhibiting arousal pathways and diverting energy from reproduction to survival.[5][9] Key contributors include: Menopause and perimenopause: Estrogen drop thins vaginal tissues, reduces lubrication, and dampens libido by altering brain chemistry
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Hilty DM, Leamon MH, Lim RF et al (2006) A review of bipolar disorder in adults
Worsening Nausea Once again, it is worth noting that GLP-1s do not function because they cause nausea that discourages you from eating