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Its involvement at the intersection of metabolic regulation, stress responsiveness, and reproductive endocrinology positions it as a candidate for conditions in which these domains converge, such as menopause-associated metabolic dysfunction or stress-related eating disorders

Naunyn-Schmiedeberg's Arch Pharmacol 399 , 1327513292 (2026)

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Retatrutide offers an alternative that addresses the root cause of fat gain during bulking: excessive caloric intake