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3 Statistical analysis To assess whether the available sample was sufficient to obtain reliable results, the first step was to evaluate the power analysis, using G*power, for the variable Fat Mass, which is one of the primary outcomes

N Engl J Med 361:4051

Studies by Sumithran and colleagues have shown that weight loss triggers increases in ghrelin (the hunger hormone) and decreases in leptin (the satiety hormone), creating a biological drive to regain lost weight

Through a process called S-glutathionylation, glutathione also regulates major DNA repair proteins, such as the Ku70/Ku80 heterodimer used in Non-Homologous End Joining (NHEJ) to repair double-strand breaks