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Jan-Feb 2019;23(1):9-13

The authors attributed the increased risk to activation of cytochrome P450 2E1 by alcohol and depletion of glutathione stores by starvation or alcohol abuse

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Celastrol reduces RSL-3-induced oxidative stress and lipid peroxidation in HK-2 cells To further confirm the protective effects of celastrol against ferroptosis, we examined its impact on RSL-3-induced ferroptosis in HK-2 cells