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Although low serum B12 levels have been associated with increased bone turnover and fracture risk (9) , long-term B12 and folic acid supplementation did not improve bone mineral density (38) , or reduce osteoporotic fracture incidence in elderly individuals with elevated plasma homocysteine levels (39)

Neurologic conditions like multiple sclerosis or Parkinsons

Some reported side effects are mild and localized to the injection site (if administered via injection), such as redness, pain, or swelling

Route Intranasal Published Dose Context Appears in the search and clinic landscape, but published human exposure data is absent