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But lesser amounts didn't trigger negative effects, which is why the scientists recommended a maximum single dose of 0.4 grams per kilogram of body weight and a maximum daily total of 0.9 grams per kilogram of bodyweight

Patient reported data suggest that mild to moderate nausea and related symptoms often begin to settle over 28 weeks, with further improvement over several months for many but not all patients

Researchers should document all dermatological changes carefully