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The body's robust antioxidant defense mechanism, however, can counteract this [200]

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Changes in the osmolarity of hepatocytes leads to activation of the AKR1B1 encoded aldose reductase which results in increased diversion of glucose into the pathway of fructose metabolism

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Nevertheless, reductions in gastric emptying were observed at the 1-h mark, with liraglutide 3.0 mg showing a 23% decrease and liraglutide 1.8 mg exhibiting a 13% decrease compared with the placebo [2]

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