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doi:10.1007/bf02284971
The anti-aging of this polysaccharide was related to the downregulation of daf-2 and age-1 genes expression, while up-regulating aging- and oxidative stress-associated genes expression including hsp-16.2, sod-3, skn-1, and daf-16 genes expression in the insulin/insulin-like growth factor signaling pathway (Zhang X
Wang L, Hu Y, Song B, Xiong Y, Wang J, Chen D (2021b) Targeting JAK/STAT signaling pathways in treatment of inflammatory bowel disease
Its noteworthy to mention that this adipokine not only diminishes the synthesis of the cytokine IL-17 in human CD4+/CD8+ T cells (78), but also orchestrates the modulation of IL-17A mRNA expression through the AdipoR1 receptor in T cells
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