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Feb 1 2011 Chen et al., Journal of Clinical Investigation, doi:10.1172/JCI41062 N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice Experimental study using purified human vWF, human plasma, and wild-type/ADAMTS13-deficient mice showing that N-acetylcysteine (NAC) reduces von Willebrand factor multimer size and activity

KPV is an ultra-short tripeptide derived from alpha-melanocyte stimulating hormone, researched primarily for chronic inflammation, skin disorders, and gut health support