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However, the precise mechanisms of ferroptosis in CHD have not been fully elucidated, necessitating further in-depth mechanistic investigations and the development of more effective and safer clinical intervention strategies to ultimately improve patient outcomes

Karst H, Droogers WJ, van der Weerd N, Damsteegt R, van Kronenburg N, Sarabdjitsingh RA, et al

Some studies suggest that prolonged or excessive mTOR inhibition may impair muscle protein synthesis and potentially exacerbate sarcopenia in older adults, highlighting a possible trade-off between metabolic benefits and preservation of lean massan area requiring further investigation [28]

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