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High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and multiple sclerosis ( * Probe sets were averaged when multiple probes mapped to the same gene

James et al ., 2010, "Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects"

"Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian Indians"

Besides these stage-specific effects, GHK-Cu and KPV@PPP_E also demonstrated antibacterial activity, which may further support inflammation resolution by reducing microbial burden