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A 2025 analysis of FDA adverse event reporting data found a potentially elevated risk of visionimpairment reports with semaglutide use compared with some other diabetes and weightloss medications, and it called for vigilant surveillance and further research

While the FDA continues to monitor reports of suicidal thoughts, their 2024 safety communication found no clear evidence linking these medications to suicidal ideation

Diseases such as SLE, MS, and COPD further contribute to the spectrum of microenvironmental heterogeneity, requiring tailored delivery strategies for each condition [526,527,528]

After 24 weeks of therapy weight loss was 1.7 kg and 2.56 kg among patients with mild and moderate/severe SDB, respectively