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Failure to treat primary carnitine deficiency infants promptly with intravenous glucose during periods of metabolic decompensation will result in progression to coma and death

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Upon activation by environmental signals, they bind to cis-acting elements (e.g., MYBCORE, AC-box, P-box, H-box, G-box) in target gene promoters, either independently or in complexes with other proteins, to modulate stress-responsive gene expression (Zhang et al., 2025)