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How to implement: Dosing: 20-40 grams daily (post-workout or as snack) Choose undenatured whey (cold-processed, preserves bioactive peptides) Whey protein isolate (higher protein content, lower lactose) Best sources: Grass-fed whey isolate : Highest cysteine content Undenatured whey concentrate : Preserves immunoglobulins and glutathione precursors Avoid heat-treated : Heat denatures cysteine Timing: Post-workout (supports muscle recovery + glutathione synthesis) Morning (with breakfast) For vegans: Pea protein isolate : Lower in cysteine but can be paired with NAC Hemp protein : Moderate cysteine content Evidence: A randomized trial found that 20 grams of whey protein daily for 3 months increased lymphocyte glutathione by 35% and improved immune markers in HIV patients [15]

244 In diabetic complications research, the activation of p53/SLC7A11/GSH axis causes endothelial cell ferroptosis under hyperglycemia, suggesting the important role of ferroptosis of endothelial dysfunction caused by diabetes

SGLT2 inhibitors appear more effective in mitigating glomerular hyperfiltration and lowering heart failure risk, whereas GLP-1 receptor agonists are particularly beneficial in reducing albuminuria and atherosclerotic cardiovascular events