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Glutathione synthesis is a two-step process involving the enzymes -glutamylcysteine synthetase (-GCS) and glutathione synthetase (GS)

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VLEKT is characterized by a very low total energy intake (650800 kcal per day), carbohydrate restriction to less than 30 g/day, fat intake of around 20 g/day with a preference for sources of unsaturated fats such as extra-virgin olive oil, and protein intake of 0.81.2 g/kg of reference body weight (i.e., calculated based on the patient's height) ( MAD was developed in 2003 as an alternative to the conventional KD, particularly in the context of treating drug-resistant epilepsy ( MCTKD was developed in 1971 by Huttenlocher et al