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In the TRIUMPH-1 Phase 3 trial, participants on the highest dose of retatrutide lost an average of 28.3% of their body weight at 80 weeks

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Instead of aiming immediately toward standard therapeutic dose levels, microdosing focuses on smaller medication exposure, slower escalation, and a gentler patient experience

MTC is very rare, accounting for only about 1% to 3% of all thyroid cancer cases in the UK