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The TFAP2A/NEL3 axis has also been found to promote M2 polarisation through Gln metabolism, thus providing a theoretical basis for immunotherapy targeting cancer TMEs [119]

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Below, we explain how IM8 fared in each area

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The muscle was digested in 1% collagenase in HBSS for 30 min at 37C with constant rotation

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Future research should focus on biomarker-guided, stratified trials to identify responsive subgroups ( Figure 3 )

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