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175 Traditional agents like ginger and peppermint, though not elaborated in the primary dataset, have been widely cited (e.g., Brierley & Kelber, 2011) for their ability to regulate motility through TRP channel modulation and calcium channel blockade

Notably, the metabolic benefits of dual GLP-1R/GcgR agonists have also been documented in obese non-human primates, where chronic administration of a lower dose of a GLP-1R/GcgR co-agonist vs a GLP-1R mono-agonist reduced body weight and improved glucose tolerance to a greater degree [77]

Additionally, a triple dosage may be considered in specific circumstances

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