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Neutrophils are the most abundant leukocytes in the system and play a major role in the innate immune response

Because of the theoretical benefits of maintaining antioxidant defenses to combat various acute and chronic diseases, reducing the consequences of aging and reducing tissue damage from exposure to environmental oxidants, therapeutic approaches to increase systemic and/or tissue-specific glutathione concentrations are of considerable investigational interest

Sensitive-skin users can patch test on the inner arm or behind the ear for a few days before applying to face

There are long lists of targets in this category (see previous subchapter of this article or the paper by Salillas and Sancho)