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[12] demonstrated that sKlotho inhibited the intracellular signaling of insulin/IGF-1 by preventing the phosphorylation of InsR/IGF-1R in rat hepatocytes (Fig

GLP-1 medications are generally contraindicated in people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and should be used cautiously with a history of pancreatitis

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Lv Q, Meng XF, He FF, Chen S, Su H, Xiong J, Gao P, Tian XJ, Liu JS, Zhu ZH, Huang K, Zhang C