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A pre-specified analysis of SELECT trial, showed a clinically relevant reduction in albuminuria with a net treatment benefit of 10.7% (95% CI 13.2, 8.2) in patients with albuminuria at baseline suggesting a beneficial kidney effect of once-weekly subcutaneous semaglutide 2.4 mg in patients with overweight/obesity and established CVD, without diabetes [31]

(Oxf.) 82 , 686694 (2015)

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The particularly exciting thing about this class of diabetes medications is that, in contrast to many currently available diabetes drugs that address downstream effects, these medications target the root cause of diabetes