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Ozempic (semaglutide) injection: Safety data sheet

The process as claimed in claim 7, wherein the solvent is selected from hydrocarbon solvents, ether solvents, ester solvents, polar-aprotic solvents, chloro solvents, ketone solvents, nitrile solvents, water and the like or mixtures thereof, the base is selected from organic bases and the coupling agent is selected from N,N'-dicyclohexylcarbodiimide (DCC), N,N"-diisopropylcarbodiimide (DIC), l-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC.HC1), N,N"-carbonyldiimidazole (CDI), 1- [bis(dimethylamino) methylene] - 1H- 1 ,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate (HATU), 2-( IH-benzotriazol- 1 -yl)- 1 , 1 ,3,3-tetramethyluronium hexafluorophosphate (HBTU), IH-benzotriazolium l-[bis(dimethylamino)methylene]-5- chloro-hexafluorophosphate( 1 )-3-oxide(HCTU), (benzotriazol- 1 -yloxy)tris(dimethyl amino )phosphonium hexafluoro phosphate (BOP), benzotriazol- 1-yl-oxytripyrrolidino phosphonium hexafluorophosphate (PyBOP), l-hydroxy-7-azatriazole, 1-hydroxy benzotriazole (HOBt), 1-hydroxy- 1H-1, 2, 3-triazole-4-carboxylate, O-(benzotriazol-l-yl)- N,N,N',N'-tetramethyl uranium tetrafluoroborate, N-hydroxysuccinamide, N- hydroxysulfo succinimide, ethyl cyanohydroxyiminoacetate, 7-azabenzotriazol-l- yloxy)tripyrrolidinophosphonium hexafluorophosphate, N,N,N',N'-Tetramethyl-O-(N- succinimidyl)uronium tetrafluoroborate (TSTU) or mixtures thereof

That pattern shows up in weight loss research again and again, regardless of the approach

Semaglutide also slows stomach emptying, which may help control appetite but can contribute to digestive side effects