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Methionine-R-sulfoxide reductase B1 (formerly selenoprotein R) The methionine sulfoxide reduction system is involved in the protection against oxidative stress and is especially critical for the regeneration of proteins damaged by ROS

Uses NNMTi is an enzyme overexpressed during skeletal muscle aging and is associated with the repair of damage to the NAD+ pathway, dysregulation of sirtuin1 activity, and increased senescence of muscle stem cells

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Two authors (AM and SS) independently screened study titles and abstracts to ascertain eligibility for full-text assessment, with any discrepancies resolved through consultation with a senior author (HR)