long-term use associated with osteoporosis, adrenal suppression (code separately) Immunomodulators: Azathioprine (AZA), 6-mercaptopurine (6-MP), methotrexate for maintenance of remission
Similar lean-mass proportion is not the same as builds muscle or preserves all muscle automatically. Across obesity treatment generally, lean body mass loss still occurs with weight reduction, including with GLP-1based therapies, and newer expert commentary continues to emphasize muscle preservation as a major clinical priority
Lancet 392:15191529 Gerstein HC, Colhoun HM, Dagenais GR, Diaz R, Lakshmanan M, Pais P, Probstfield J, Riesmeyer JS, Riddle MC, Rydn L, Xavier D, Atisso CM, Dyal L, Hall S, Rao-Melacini P, Wong G, Avezum A, Basile J, Chung N, Conget I, Cushman WC, Franek E, Hancu N, Hanefeld M, Holt S, Jansky P, Keltai M, Lanas F, Leiter LA, Lopez-Jaramillo P, Cardona Munoz EG, Pirags V, Pogosova N, Raubenheimer PJ, Shaw JE, Sheu WH, Temelkova-Kurktschiev T (2019) REWIND Investigators
Biochemistry 2001