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For context on filler volume needs: McKinsey 2025 reported that 61% of GLP-1 aesthetic patients have lost 11 to 30% of their body weight, a magnitude of loss that typically requires multiple syringes for full initial correction (clinical practice patterns reported by aesthetic providers suggest 4 to 8 syringes initially, then 2 to 4 syringes annually for maintenance, though syringe counts vary substantially by individual anatomy and zones treated)

More consistent appetite suppression: Stable blood levels produce more consistent appetite reduction