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An analysis of real-world integrated pharmacy and medical claims data by leading pharmacy benefit manager (PBM) Prime Therapeutics LLC (Prime), and Magellan Rx Management, (Magellan Rx), a Prime Therapeutics company, shows that 68 percent of individuals who newly started glucagon-like peptide-1 agonist (GLP-1a) drugs for weight loss were no longer taking the drug after one year
Since most studies did not include depression/anxiety patients of the same severity, it was difficult to conduct subgroup analysis based on baseline disease severity
The search involved the following query: COVID-19 treatment OR Management AND Long COVID AND Post-acute sequela of SARS-CoV-2 (PASC) AND Post-COVID-19 condition (PCC) OR Syndrome
Others point to the prolonged half-life of newer GLP-1 drugs, which means the receptors are being stimulated continuously rather than in the pulsatile pattern that natural GLP-1 produces
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