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In one trial (NCT00859898), 638 patients randomized to 1 of 3 treatment arms following a 1-week lead-in period received: FARXIGA 10 mg plus metformin XR (up to 2,000 mg per day), FARXIGA 10 mg plus placebo, or metformin XR (up to 2,000 mg per day) plus placebo
de Sousa Melo, S.R., et al
Yamazaki, S., Su, Y., Maruyama, A., Makinoshima, H., Suzuki, J., Tsuboi, M