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1 Weight loss results: Semaglutide 0.5 mg: -4.6 kg vs dulaglutide 0.75 mg: -2.3 kg Semaglutide 1.0 mg: -6.5 kg vs dulaglutide 1.5 mg: -3.0 kg Treatment difference: approximately double the weight loss with semaglutide at both dose levels Blood sugar control was also superior with semaglutide at all dose comparisons: Cardiovascular outcomes Both medications have demonstrated cardiovascular benefits, though in different trials

Amycretin is equally important because it gives Novo Nordisk another GLP-1 plus amylin asset, including oral development potential

doi: 10.1038/oby.2012.67 260 JorgensenRKubaleVVreclMSchwartzTWEllingCE