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Per the preclinical safety profile, this remains far below any dose associated with toxicity in animals 1

[PubMed] [Google Scholar] 6.Shimasaki S, Ling N

Additionally, environmental factors such as iodine excess or deficiency, smoking, stress, exposure to chemicals, medications (e.g., amiodarone, interferon-), and some viral/bacterial infections can alter gene expression patterns through epigenetic mechanisms and trigger autoimmune processes