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The European prevalence of this condition is estimated at 19:100.000 with about 300 cases recognized (Wieser)

Pharmacodynamic and efficacy analysis of the BRAF inhibitor dabrafenib (GSK436) in combination with the MEK inhibitor trametinib (GSK212) in patients with BRAFV600 mutant colorectal cancer (CRC)

Spicy foods, caffeine, alcohol, chocolate, and carbonated drinks may trigger or worsen symptoms