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Subpopulation analysis in STEP 1, which involved only non-diabetic obese patients, revealed that weekly GLP1/GIP medication eliminated 6.99 kg and 0.27 kg more total and visceral fat mass, respectively, than placebo as measured by dual emission X-ray absorptiometry

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Visible improvements typically at 46 weeks

This vaccine, called Lipo@HEV is the product of combining B16F10, 4T1 and CT26 (epithelial, breast and colon) tumor cell lines with the biocompatible and coadjuvant outer membrane vesicle from Akkermansia muciniphila (Akk-OMV) and loaded with gene therapy plasmid encoding PD-L1 binding domain in a trimeric form that acts as a trap