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In a meta-analysis and systematic review published in BMC Endocrine Disorders in 2023 , researchers found that, among 840 women with PCOS across 11 randomized controlled trials, the use of GLP-1 was associated with an improvement in the rate of spontaneous pregnancy

In addition to reductions in body weight, abdominal fat and liver fat, retatrutide treatment was associated with improvements in insulin sensitivity, lipid metabolism and adipocyte hormones

This process is critical for maintaining endurance and preventing fatigue during physical activity

While peptide therapies operate under medical supervision, supplement stacks apply these insights through nutritional strategies