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Research also suggests that allulose can trigger GLP-1 release, which could contribute to weight loss , but this effect appears modest compared to calorie reduction, which remains the primary driver

Given that GPX4 deficiency leads directly to cell death 35 , we established stable GPX4 protein knockdown in Raji cells

once per week

The primary endpoint, MACE, was the time to first occurrence of a three-part composite outcome which included cardiovascular death, non-fatal MI and non-fatal stroke