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Tumor diameters were measured with digital calipers at multiple time points (days 3, 5, 7, 9, and 11), and the tumor area (in mm 2 ) was calculated with the following formula: area = 3.14 width length/4

Substantial human trial data for full-length TB-4 (corneal-healing Phase 2/3 as RGN-259, plus cardiac and wound-repair programs), with clean Phase 1 safety. Cosmetic dosing is extrapolated from these programs

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Added to this are factors such as the chronic stress , the systemic inflammation and toxic load , which increase the need for micronutrients and further reduce their assimilation