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INTRODUCTION The most prevalent adverse effects associated with GLP-1 RAs include gastrointestinal disturbances, such as nausea, vomiting, diarrhea, and constipation [6,7]

As levels continue to drop, symptoms become more noticeable

Follow-up studies for 4 and 7 years after the intervention with 500 mg/day for 9 months showed that sustained cognitive benefit was associated with potential improvements in associated white matter microstructure in the choline group (170, 171), which suggests that choline supplementation has the potential to alter brain architecture